CKMT2 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-32929

Overview

Synonyms CKMT 2,Basic-type mitochondrial creatine kinase,CKMT2,CPK,Creatine kinase mitochondrial 2,Creatine kinase mitochondrial 2 (sarcomeric),Creatine kinase S-type,creatine kinase S-type,mitochondrial,Creatine kinase,sarcomeric mitochondrial,KCRS,Mib CK,Mib-CK,mitochondrial,OTTHUMP00000147542,S-MtCK,Sarcomeric mitochondrial creatine kinase,SMTCK
Swissprot P17540
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the Internal region of human sMtCK
Application WB,IHC-p,IF,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.

 

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