Claudin 1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-30939

Overview

Synonyms Claudin-1,Claudin1,CLD 1,CLD1,CLD1,CLDN 1,Cldn1,ILVASC,SEMP 1,SEMP1,Senescence associated epithelial membrane protein 1,Senescence associated epithelial membrane protein,Senescence-associated epithelial membrane protein
Swissprot O95832
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the C-terminal region of human Claudin-1
Application WB,IHC-p,IF,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

 

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