CLDND1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-10251

Overview

Synonyms C3orf4,Chromosome 3 open reading frame 4,Claudin domain containing 1,Claudin domain containing 1 protein,GENX 3745,Membrane protein GENX3745,MGC111162,MGC3316,MGC9861,OTTHUMP00000217407,OTTHUMP00000217408,OTTHUMP00000217423,OTTHUMP00000217424,OTTHUMP00000217562,OTTHUMP00000217563,OTTHUMP00000217584,OTTHUMP00000217585,OTTHUMP00000217586,OTTHUMP00000217587,OTTHUMP00000217609,OTTHUMP00000217610,OTTHUMP00000217611,OTTHUMP00000217622,OTTHUMP00000217623,OTTHUMP00000217625,OTTHUMP00000217627,OTTHUMP00000217628,OTTHUMP00000217638
Swissprot Q9NY35
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human CLDND1
Application WB,IHC,ELISA
Recommended dilution WB 1:200-1:1000, IHC 1:50-1:200
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background CLDND1 (claudin domain containing 1), also known as C3orf4 or HSPC174, is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

 

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