CNTFR Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-60766

Overview

Synonyms Ciliary neurotrophic factor receptor alpha ,Ciliary neurotrophic factor receptor,Ciliary neurotrophic factor receptor subunit alpha,CNTF receptor subunit alpha,CNTFR Alpha,CNTFR,CNTFR-alpha,CNTFR
Swissprot P26992
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human CNTFR
Application WB
Recommended dilution WB 1:400 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

 

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