CR1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16356

Overview

Synonyms C3 binding protein,C3b/C4b receptor,C3BR,C4BR,CD 35,CD35,CD35 antigen,complement component (3b/4b) receptor 1 (Knops blood group),complement component (3b/4b) receptor 1 including Knops blood group system,Complement component receptor 1,Complement receptor 1,Complement receptor type 1,CR 1,CR1,CR1,KN,Knops blood group antigen
Swissprot P17927
Source Rabbit
Reactivity Human
Immunogen Synthetic peptide of human CR1
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 1.4mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis.

 

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