CYP1B1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-31088

Overview

Synonyms Aryl hydrocarbon hydroxylase,CP1B,CP1B1,Cyp1b1,CYPIB1,Cytochrome P450 1B1,Cytochrome P450 family 1 subfamily B polypeptide 1,Cytochrome P450 subfamily I (dioxin inducible) polypeptide 1 (glaucoma 3 primary infantile),Flavoprotein linked monooxygenase,GLC3A,Microsomal monooxygenase,P4501B1,Xenobiotic monooxygenase
Swissprot Q16678
Source Rabbit
Reactivity Human
Immunogen Synthesized peptide derived from the Internal region of human CYP1B1.
Application WB,ELISA
Recommended dilution WB 1:500-1:2000, ELISA 1:40000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.

 

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