CYP2C9 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-14908

Overview

Synonyms (R)-limonene 6-monooxygenase,(S)-limonene 6-monooxygenase,(S)-limonene 7-monooxygenase,CP2C9,CPC9,CYP2C,CYP2C10,CYP2C9,CYPIIC9,cytochrome P-450 S-mephenytoin 4-hydroxylase,Cytochrome P-450MP,Cytochrome P450 2C9,Cytochrome P450 MP-4,Cytochrome P450 MP-8,Cytochrome P450 PB-1,Cytochrome P450,family 2,subfamily C,polypeptide 9,Cytochrome p4502C9,flavoprotein-linked monooxygenase,MGC149605,MGC88320,microsomal monooxygenase,OTTHUMP00000020135,P450 MP,P450 PB 1,P450 PB1,P450IIC9,P450MP,S mephenytoin 4 hydroxylase,S-mephenytoin 4-hydroxylase,xenobiotic monooxygenase
Swissprot P11712
Source Rabbit
Reactivity Human
Immunogen Recombinant protein of human CYP2C9
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.7mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

 

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