DTX2 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-10281

Overview

Synonyms Deltex 2,deltex homolog 2 (Drosophila),deltex,Drosophila,homolog of,2,Deltex2,DTX2,DTX2,hDTX2,Highly similar to hPMSR6 [H.sapiens],KIAA1528,Probable E3 ubiquitin-protein ligase DTX2,Protein deltex 2,Protein deltex-2,RING finger protein 58,RNF58,Zinc ion binding protein
Swissprot Q86UW9
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human DTX2
Application IHC,ELISA
Recommended dilution IHC 1:10-1:50
Concentration 0.5mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background DTX2 functions as an E3 ubiquitin ligase. Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

 

You recently viewed

Clear recently viewed
Print Friendly and PDF