EIF6 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-14982

Overview

Synonyms b(2)gcn,B(2)GCN homolog,B4 integrin interactor,Binding protein of beta-4 integrin,CAB,eIF-6,EIF3A,EIF6,Eukaryotic translation initiation factor 3A,Eukaryotic translation initiation factor 6,IF6,ITGB4BP,OK/SW-cl.27,p27 beta 4 integrin binding protein,p27(BBP),p27BBP,RP4-614O4.1
Swissprot P56537
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human EIF6
Application WB,ELISA
Recommended dilution WB 1:200-1:1000
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.

 

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