ELAVL3 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16549

Overview

Synonyms ELAV (embryonic lethal abnormal vision Drosophila) like 3 (Hu antigen C),ELAV like protein 3,ELAV-like protein 3,ELAV3,Elavl3,Embryonic lethal,abnormal vision,drosophila,homolog-like,Hu antigen C,Hu-antigen C,HuC,HUCL,MGC20653,Paraneoplastic cerebellar degeneration associated antigen,Paraneoplastic cerebellar degeneration-associated antigen,Paraneoplastic limbic encephalitis antigen 21,PLE21
Swissprot Q14576
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human ELAVL3
Application WB,IHC,ELISA
Recommended dilution WB 1:200-1:1000, IHC 1:25-1:100
Concentration 0.6mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

 

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