ERVFRD-1 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-63289

Overview

Synonyms Endogenous Retrovirus Group FRD Member 1 Envelope,Endogenous Retrovirus Group FRD Member 1,HERV-FRD_6p24.1 Provirus Ancestral Env Polyprotein,Envelope Polyprotein,ERVFRDE1,HERV-FRD,HERV-FRD Provirus Ancestral Env Polyprotein,Endogenous Retrovirus Group FRD, Member 1,Syncytin 2,HERV-W/FRD,Syncytin-2,GLLL6191,UNQ6191,EnvFRD
Swissprot P60508
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human ERVFRD-1
Application WB
Recommended dilution WB 1:1000 - 1:4000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

 

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