ESRRG Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-14996

Overview

Synonyms DKFZp781L1617,ERR 3,ERR G2,ERR gamma 2,ERR gamma-2,ERR3,ERR3,ERRG 2,ERRG2,ERRgamma,ESRRG,Estrogen receptor related protein 3,Estrogen receptor-related protein 3,Estrogen-related receptor gamma,FLJ16023,KIAA0832,NR3B3,Nuclear receptor subfamily 3 group B member 3
Swissprot P62508
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human ESRRG
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
Concentration 0.5mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways.

 

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