EVPL Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-63301

Overview

Synonyms 210 kDa cornified envelope,210 kDa cornified envelope precursor protein,210 kDa paraneoplastic pemphigus antigen,EVPK,P210
Swissprot Q92817
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human EVPL
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. This gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against the encoded protein.

 

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