FA2H Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-36458


Synonyms FA2H,FA2H,FAAH,FAH1,Fatty acid 2 hydroxylase,Fatty acid 2-hydroxylase,Fatty acid alpha hydroxylase,Fatty acid alpha-hydroxylase,Fatty acid hydroxylase domain containing 1,FAXDC1,FLJ25287,SCS7,Spastic paraplegia 35 (autosomal recessive),SPG35
Swissprot Q7L5A8
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from human FA2H
Application WB,ELISA
Recommended dilution WB 1:500-2000, ELISA 1:10000-20000
Concentration 1mg/mL
Clonality Polyclonal


Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Background FA2H (Fatty Acid 2-Hydroxylase) is a Protein Coding gene. Diseases associated with FA2H include Spastic Paraplegia 35, Autosomal Recessive and Spastic Paraplegia 35. Among its related pathways are fatty acid alpha-oxidation III and Metabolism. GO annotations related to this gene include oxidoreductase activity and heme binding.This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.


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