FAM107A Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-15012

Overview

Synonyms Down regulated in renal cell carcinoma 1,Down-regulated in renal cell carcinoma 1,Downregulated in renal cell carcinoma,DRR1,F107A,FAM107A,Family with sequence similarity 107,member A,FLJ30158,FLJ45473,Protein FAM107A,Protein TU3A,TU3A
Swissprot O95990
Source Rabbit
Reactivity Human
Immunogen Recombinant protein of human FAM107A
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.5mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background FAM107B is a 131 amino acid protein that is encoded by a gene that maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.

 

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