Overview
| Synonyms | AGO,Archipelago,Archipelago homolog,Archipelago,Drosophila,homolog of,CDC4,CDC4,S.cerevisiae,homolog of,DKFZp686F23254,F box and WD 40 domain protein 7 (archipelago homolog,Drosophila),F box and WD 40 domain protein 7,F box and WD repeat domain containing 7,F box protein FBW7,F box protein FBX30,F box protein SEL 10,F box protein SEL10,F-box and WD repeat domain containing 7,E3 ubiquitin protein ligase,F-box and WD-40 domain-containing protein 7,F-box protein FBX30,F-box/WD repeat-containing protein 7,FBW6,FBW7,FBX30,FBXO30,FBXW6,FBXW7,FBXW7,FLJ16457,hAgo,hCdc4,Homolog of C elegans sel 10,Homolog of C.elegans sel10,SEL 10,SEL-10,SEL10 |
| Swissprot | Q969H0 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human FBXW7 |
| Application | IHC,ELISA |
| Recommended dilution | IHC 1:100-1:300 |
| Concentration | 0.3mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | |
| Tissue specificity | |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats. |
