FBXW7 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-11064

Overview

Synonyms AGO,Archipelago,Archipelago homolog,Archipelago,Drosophila,homolog of,CDC4,CDC4,S.cerevisiae,homolog of,DKFZp686F23254,F box and WD 40 domain protein 7 (archipelago homolog,Drosophila),F box and WD 40 domain protein 7,F box and WD repeat domain containing 7,F box protein FBW7,F box protein FBX30,F box protein SEL 10,F box protein SEL10,F-box and WD repeat domain containing 7,E3 ubiquitin protein ligase,F-box and WD-40 domain-containing protein 7,F-box protein FBX30,F-box/WD repeat-containing protein 7,FBW6,FBW7,FBX30,FBXO30,FBXW6,FBXW7,FBXW7,FLJ16457,hAgo,hCdc4,Homolog of C elegans sel 10,Homolog of C.elegans sel10,SEL 10,SEL-10,SEL10
Swissprot Q969H0
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human FBXW7
Application IHC,ELISA
Recommended dilution IHC 1:100-1:300
Concentration 0.3mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats.

 

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