Overview
| Synonyms | ABPL,Actin binding like protein,FIlamin 2,Filamin C,FLN2,Gamma filamin |
| Swissprot | Q14315 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant Protein of human FLNC |
| Application | WB |
| Recommended dilution | WB 1:500 - 1:2000 |
| Concentration | 1mg/ml |
| Clonality | Polyclonal |
Properties
| Cellular localization | |
| Tissue specificity | |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background | This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. |
