FMR1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-15046

Overview

Synonyms FMR 1,Fmr1,Fmr1 gene,FMR1,FMRP,Fragile X mental retardation 1,Fragile X mental retardation 1 protein,Fragile X mental retardation protein 1,Fragile X mental retardation protein,fragile X mental retardation syndrome-related protein 1,fragile X mental retardation,autosomal homolog 1,FRAXA,fxr1,MGC87458,POF,POF1,Protein FMR-1,Protein FMR1,wu:fb16f11,wu:fd18c10,zgc:66226
Swissprot Q06787
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human FMR1
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.5mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

 

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