FOXB1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-12418

Overview

Synonyms FKH 5,FKH5,Forkhead box B1,Forkhead box protein B1,FOX B1,FOXB 1,HFKH 5,HFKH-5,HFKH5,Transcription factor FKH 5,Transcription factor FKH5
Swissprot Q99853
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human FOXB1
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.

 

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