FZD8 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16118

Overview

Synonyms Frizzled 8 seven transmembrane spanning receptor,frizzled 8,seven transmembrane spanning receptor,Frizzled family receptor 8,frizzled homolog 8 (Drosophila),Frizzled homolog 8,Frizzled-8,FZ 8,Fz-8,FZ8,FZD 8,FZD8,FZD8,hFZ 8,hFz8,HGNC4046,Homolog of Drosophila Frizzled 8
Swissprot Q9H461
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthetic peptide of human FZD8
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

 

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