GABPA Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-64119

Overview

Synonyms E4TF 1A,E4TF1 60,E4TF1A ,GA binding protein alpha chain,GA binding protein transcription factor alpha subunit 60kDa,GA binding protein transcription factor alpha subunit,GA-binding protein alpha chain,GABP A,GABP alpha subunit,GABP subunit alpha,Gabpa,GABPA,Human nuclear respiratory factor 2 subunit alpha,NFT 2,NFT2,NRF 2,NRF 2A,NRF2,NRF2A,Nuclear respiratory factor 2 alpha subunit,Nuclear respiratory factor 2 subunit alpha,RCH04A07,Transcription factor E4TF1 60,Transcription factor E4TF1-60
Swissprot Q06546
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen A synthetic peptide of human GABPA
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.

 

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