GARS Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-64547

Overview

Synonyms AP 4 A synthetase,Charcot Marie Tooth neuropathy 2D,Charcot Marie Tooth neuropathy neuronal type D,CMT2D ,Diadenosine tetraphosphate synthetase,DSMAV ,EC 6.1.1.14,Glycine tRNA ligase,Glycyl tRNA synthetase,GlyRS ,HMN5,SMAD1
Swissprot P41250
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human GARS
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.

 

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