GFRA3 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-15686

Overview

Synonyms GDNF family receptor alpha 3,GDNF family receptor alpha-3,GDNF receptor alpha-3,GDNFR-alpha-3,GDNFR3,GFR-alpha-3,GFRA3,GFRA3,Glial cell line derived neurotrophic factor receptor alpha 3,GPI linked receptor,OTTHUMP00000159486,OTTHUMP00000224020
Swissprot O60609
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthetic peptide of human GFRA3
Application IHC,ELISA
Recommended dilution IHC 1:50-1:150
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression.

 

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