GK1/3 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-31543

Overview

Synonyms GK,Glycerol kinase,GK,Glycerokinase,ATP:glycerol 3-phosphotransferase,GK3P,GKP3,GKTB,Putative glycerol kinase 3,GK 3,Glycerokinase 3,ATP:glycerol 3-phosphotransferase 3,Glycerol kinase,testis specific 1
Swissprot P32189,Q14409
Source Rabbit
Reactivity Human
Immunogen Synthesized peptide derived from the N-terminal region of human GK1/3
Application WB,IHC-p,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Background The protein encoded by GK belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. GK (Glycerol Kinase) is a Protein Coding gene. Diseases associated with GK include Glycerol Kinase Deficiency and Glycerol Kinase Deficiency, Adult Form. Among its related pathways are triacylglycerol biosynthesis and Glycerophospholipid Biosynthetic Pathway. GO annotations related to this gene include kinase activity and glycerol kinase activity. An important paralog of this gene is GK3P. GK3P (Glycerol Kinase 3 Pseudogene) is a Pseudogene. An important paralog of this gene is GK.

 

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