GRK2 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-31617

Overview

Synonyms ADRBK1,Adrenergic beta receptor kinase 1,ARBK1,BARK,BARK1,Beta adrenergic receptor kinase 1,Beta ARK 1,Beta ARK1,Beta-adrenergic receptor kinase 1,Beta-ARK-1,FLJ16718,G protein coupled receptor kinase 2,G-protein coupled receptor kinase 2,GRK2
Swissprot P25098
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the C-terminal region of human GRK 2
Application WB,IHC-p,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Background Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.

 

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