GSR Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-63620

Overview

Synonyms GLR1,GLUR,Glutathione reductase,Glutathione reductase mitochondrial,Glutathione reductase,mitochondrial,GR,Gr1,GRase,GRD 1,GRD1,GSHR,GSR,MGC78522
Swissprot P00390
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human GSR
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

 

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