GSTA3 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-15087

Overview

Synonyms Glutathione S alkyltransferase A3,Glutathione S aralkyltransferase A3,Glutathione S aryltransferase A3,Glutathione S transferase A3 3,Glutathione S transferase A3,glutathione S transferase A3 subunit,Glutathione S transferase alpha 3,Glutathione S transferase alpha type (Ya),glutathione S transferase Yc 1,glutathione S transferase Yc1 subunit,Glutathione S-transferase A3,Glutathione S-transferase A3-3,Glutathione S-transferase Ya3,Glutathione S-transferase Yc,glutathione transferase A3 subunit,Glutathione transferase alpha 3,GST 2 2,GST AA,GST class alpha,GST class alpha member 3,GST class-alpha member 3,GST Yc1,GSTA 3,GSTA3 3,Gsta3,GSTA3-3,GSTA3,Gstyc,GTA 3,GTA3,MGC22232,S (hydroxyalkyl)glutathione lyase A3,Yc1
Swissprot Q16772
Source Rabbit
Reactivity Human
Immunogen Recombinant protein of human GSTA3
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:25-1:100
Concentration 0.3mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. 

 

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