HACE1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16474

Overview

Synonyms E3 ubiquitin-protein ligase HACE1,HACE 1,HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1,KIAA1320
Swissprot Q8IYU2
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthetic peptide of human HACE1
Application IHC,ELISA
Recommended dilution IHC 1:100-1:200
Concentration 1.5mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background HACE1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1), also known as KIAA1320, is a 909 amino acid protein that localizes to both the cytoplasm and the endoplasmic reticulum and contains one HECT domain and six ANK repeats. Expressed in kidney, heart and brain, HACE1 functions as an E3 ubiquitin-protein ligase that interacts with the proteasome and is thought to play a role in protein degradation. HACE1 is downregulated in Wilms tumor, suggesting a possible role in tumor suppression.

 

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