HAS1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-13287

Overview

Synonyms HA synthase 1,HAS,HAS1,HuHAS1,Hyaluronan synthase 1,Hyaluronate synthase 1,Hyaluronic acid synthase 1,HYAS1
Swissprot Q92839
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human HAS1
Application WB,IHC,ELISA
Recommended dilution WB 1:200-1:1000, IHC 1:50-1:200
Concentration 0.9mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Hyaluronan or hyaluronic acid (HA) is a higHuman, Mouseolecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis.

 

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