HCFC1 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-60469

Overview

Synonyms C1 factor,CFF,HCF 1,HCF,HCF C-terminal chain 6,HCF-1,HCF1,Hcfc1,HCFC1,HFC1,Host cell factor 1,Host cell factor,Host cell factor C1 (VP16 accessory protein),Host cell factor C1,MGC70925,MRX3,VCAF,VP16 accessory protein
Swissprot P51610
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human HCFC1
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

 

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