HEXIM2 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-65366

Overview

Synonyms Hexamethylene bis-acetamide-inducible protein 2,Hexamthylene bis-acetamide inducible 2 ,HEXI2,hexim 2,HEXIM2,L3,Protein HEXIM2
Swissprot Q96MH2
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human HEXIM2
Application WB
Recommended dilution WB 1:200 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants.

 

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