HINT1 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-63305

Overview

Synonyms Adenosine 5' monophosphoramidase,Adenosine 5''-monophosphoramidase,HINT 1,HINT1,HINT1,Histidine triad nucleotide binding protein 1,Histidine triad nucleotide-binding protein 1,PKCI 1,PKCI-1,PKCI1,PRKCNH1,Protein kinase C inhibitor 1,Protein kinase C interacting protein 1,Protein kinase C-interacting protein 1
Swissprot P49773
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human HINT1
Application WB
Recommended dilution WB 1:1000 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a protein that hydrolyzes purine nucleotide phosphoramidates substrates, including AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif. This gene is considered a tumor suppressor gene. In addition, mutations in this gene can cause autosomal recessive neuromyotonia and axonal neuropathy. There are several related pseudogenes on chromosome 7. Several transcript variants have been observed.

 

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