HOXB8 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-13301

Overview

Synonyms Homeobox B8,Homeobox protein Hox B8,Homeobox protein Hox-2.4,Homeobox protein Hox-2D,Homeobox protein Hox-B8,Homeobox protein HoxB8,HOX 2,Hox 2.4,HOX 2D,HOX B8,HOX2,Hox2.4,HOX2D,Hoxb8,HXB8
Swissprot P17481
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human HOXB8
Application WB,ELISA
Recommended dilution WB 1:200-1:1000
Concentration 0.8mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

 

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