HTR3A Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-32955

Overview

Synonyms 5 HT 3,5 HT3 receptor,5 HT3A,5 HT3A receptor,5 HT3RA,5 hydroxytryptamine (serotonin) receptor 3A,5-HT-3,5-HT3-A,5-HT3A,5-HT3R,5-hydroxytryptamine receptor 3,5-hydroxytryptamine receptor 3A,5HT receptor,5HT3 serotonin receptor,5HT3A,5HT3R,HTR3,Htr3a,Serotonin receptor 3A,Serotonin-gated ion channel receptor 3a,Serotonin-gated ion channel receptor
Swissprot P46098
Source Rabbit
Reactivity Human
Immunogen Synthesized peptide derived from the Internal region of human SR-3A
Application WB,IHC-p,IF,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

 

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