IDH1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-30163

Overview

Synonyms Cytosolic NADP isocitrate dehydrogenase,Cytosolic NADP-isocitrate dehydrogenase,Epididymis luminal protein 216,Epididymis secretory protein Li 26,HEL-216,HEL-S-26,ICDH,IDCD,IDH,IDH1,IDHC,IDP,IDPC,Isocitrate dehydrogenase (NADP(+)) 1 cytosolic,Isocitrate dehydrogenase [NADP] cytoplasmic,Isocitrate dehydrogenase 1 (NADP+) soluble,NADP dependent isocitrate dehydrogenase cytosolic,NADP dependent isocitrate dehydrogenase peroxisomal,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase,PICD
Swissprot O75874
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the N-terminal region of human IDH1.
Application WB,IHC-p,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000-1:20000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence.

 

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