IDH3G Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-14638

Overview

Synonyms H IDHG,IDH gamma,IDH3G,IDH3G,Isocitrate dehydrogenase [NAD] subunit gamma,Isocitrate dehydrogenase [NAD] subunit gamma,mitochondrial,Isocitrate dehydrogenase 3 (NAD+) gamma,Isocitric dehydrogenase,Isocitric dehydrogenase subunit gamma,mitochondrial,NAD (H) specific isocitrate dehydrogenase gamma subunit,NAD(+) specific ICDH,NAD(+)-specific ICDH subunit gamma,NAD+ specific ICDH,OTTHUMP00000025984,OTTHUMP00000025985,OTTHUMP00000025987,OTTHUMP00000025988,OTTHUMP00000214764
Swissprot P51553
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human IDH3G
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:25-1:100
Concentration 0.3mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. 

 

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