IKBKAP Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-63276

Overview

Synonyms DKFZp781H1425,DYS,Dysautonomia (Riley Day syndrome hereditary sensory autonomic neuropathy type III),Elongator complex protein 1,ELP 1,ELP1,ELP1,FD,FLJ12497,IKAP,IkappaB kinase complex associated protein,IkappaB kinase complex-associated protein,ikbkap,IKI 3,IKI3,IKK complex associated protein,IKK complex-associated protein,Inhibitor of kappa light polypeptide gene enhancer in B cells kinase complex associated protein,OTTHUMP00000063889,p150,TOT 1,TOT1
Swissprot O95163
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human IKBKAP
Application WB
Recommended dilution WB 1:1000 - 1:4000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.

 

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