IL1RN Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-60596

Overview

Synonyms DIRA,F630041P17Rik,ICIL 1RA,ICIL-1RA,ICIL1RA,IL-1ra,IL-1ra3,IL-1RN,IL1 inhibitor,IL1F3,IL1RA,IL1RA,IL1RN (IL1F3),IL1RN,Interleukin 1 receptor antagonist,Interleukin-1 receptor antagonist protein,Intracellular IL 1 receptor antagonist type II,Intracellular interleukin 1 receptor antagonist (icIL 1ra),IRAP,MGC10430,MVCD4,Type II interleukin 1 receptor antagonist
Swissprot P18510
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human IL1RN
Application WB,IF
Recommended dilution WB 1:500 - 1:2000 IF 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

 

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