INVS Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-63340

Overview

Synonyms INV ,Inversion of embryo turning homolog ,inversion of embryonic turning,INVS,Nephrocystin 2,Nephrocystin-2,Nephrocystin2,nephronophthisis 2 (infantile),NPH2 ,NPHP2
Swissprot Q9Y283
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human INVS
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

 

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