KAT2B Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-32520

Overview

Synonyms CAF,CREBBP associated factor,GCN5,GCN5L,GCN5L1,Histone acetylase PCAF,Histone acetyltransferase KAT2B,Histone acetyltransferase PCAF,K(lysine) acetyltransferase 2B,KAT2B,KAT2B,Lysine acetyltransferase 2B,P,P/CAF,p300/CBP associated factor,P300/CBP-associated factor,Pcaf
Swissprot Q92831
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the C-terminal region of human PCAF
Application WB,IHC-p,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.

 

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