KCNJ4 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-31873

Overview

Synonyms Hippocampal inward rectifier,Hippocampal inward rectifier potassium channel,HIR,HIRK2,HRK1,Inward rectifier K(+) channel Kir2.3,Inward rectifier K+ channel Kir2.3,Inward rectifier potassium channel 4,Inward rectifier potassium channel Kir 2.3,inwardly rectifying subfamily J member 4,IRK-3,IRK3,IRK4,KCNJ 4,Kcnj4,Kir2.3,MGC142066,MGC142068,OTTHUMP00000028922,Potassium channel,Potassium channel inwardly rectifying subfamily J member 4,Potassium inwardly rectifying channel J4,Potassium inwardly rectifying channel subfamily J member 4
Swissprot P48050
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the Internal region of human KIR2.3
Application WB,ELISA
Recommended dilution WB 1:500-1:2000, ELISA 1:40000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Background Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.

 

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