KLRC4 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-65113

Overview

Synonyms killer cell lectin-like receptor subfamily C, member 4,KLRC4,NK cell receptor F,NKG2 F,NKG2-F type II integral membrane protein,NKG2-F-activating NK receptor,NKG2F,NKG2F
Swissprot O43908
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human KLRC4
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene is a member of the NKG2 group of genes that are expressed primarily in natural killer (NK) cells. These family members encode transmembrane proteins that are characterized by a type II membrane orientation (have an extracellular C-terminus) and the presence of a C-type lectin domain. This family member is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. Read-through transcription exists between this gene and the downstream KLRK1 (killer cell lectin-like receptor subfamily K, member 1) family member.

 

You recently viewed

Clear recently viewed
Print Friendly and PDF