L-Selectin Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-30117

Overview

Synonyms A.11,AI528707,CD62 antigen ligand,CD62 antigen-like family member L,CD62L,gp90-MEL,IgA nephropathy,susceptibility to,included,L Selectin,L-selectin,LAM-1,LAM1,LECAM1,LEU8,Leukocyte adhesion molecule 1,Leukocyte surface antigen Leu-8,Leukocyte-endothelial cell adhesion molecule 1,Lnhr,LSEL,Ly-22,Ly-m22,Lyam-1,LYAM1,LYAM1,Lymph node homing receptor,Lymphocyte adhesion molecule 1,Lymphocyte antigen 22,Lymphocyte surface MEL-14 antigen,MEL-14,Pln homing receptor,PLNHR,Selectin L,Selectin,lymphocyte,SELL,TQ1
Swissprot P14151
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the Internal region of human L-Selectin.
Application WB,ELISA
Recommended dilution WB 1:500-1:2000, ELISA 1:20000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Background This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.

 

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