LAMA3 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-15745

Overview

Synonyms E170,Epiligrin 170 kDa subunit,Epiligrin subunit alpha,Kalinin subunit alpha,LAMA3,LAMA3A,Laminin 5 alpha3,Laminin A3,laminin alpha 3,laminin alpha3,Laminin subunit alpha-3,Laminin-5 subunit alpha,Laminin-6 subunit alpha,Laminin-7 subunit alpha,laminin5 alpha 3,Laminin5 alpha3,LAMNA,LOCS,Nicein subunit alpha
Swissprot Q16787
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human LAMA3
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 0.4mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. The protein encoded by this gene is the alpha-3 subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

 

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