LDOC1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-15168

Overview

Synonyms BCUR1,Breast cancer up regulated 1,Breast cancer upregulated 1,Gm366,Ldoc1,LDOC1,Leucine zipper down regulated in cancer 1,Leucine zipper protein down regulated in cancer cells,Leucine zipper protein down regulated in cancer cells,Leucine zipper protein down-regulated in cancer cells,Mar7,Mart7,Protein LDOC1,RGD1565644
Swissprot O95751
Source Rabbit
Reactivity Human
Immunogen Recombinant protein of human LDOC1
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.4mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

 

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