LZTFL1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-15183

Overview

Synonyms 5530402H04Rik,6130400H19Rik,AI414725,AW048545,BBS17,DKFZp686H2076,FLJ36386,Leucine zipper transcription factor like 1,Leucine zipper transcription factor like protein 1,Leucine zipper transcription factor-like protein 1,LZTFL 1,Lztfl1,Lztfl1 leucine zipper transcription factor-like 1,LZTL1,MGC106871,MGC108960,Putative uncharacterized protein DKFZp686H2076
Swissprot Q9NQ48
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human LZTFL1
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:25-1:100
Concentration 0.3mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants.

 

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