LZTS1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16579

Overview

Synonyms F37,F37/esophageal cancer related gene coding leucine zipper motif,F37/esophageal cancer-related gene-coding leucine-zipper motif,Fez1,Leucine zipper putative tumor suppressor 1,Lzts1,LZTS1,Psdzip70
Swissprot Q9Y250
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthetic peptide of human LZTS1
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 0.3mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.

 

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