MAP4K2 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-10897

Overview

Synonyms B lymphocyte serine/threonine protein kinase,B lymphocyte serine/threonine-protein kinase,BL44,GC kinase,GCK,Germinal center kinase,germinal centre kinase (GC kinase),M4K2,Map4k2,MAPK/ERK kinase kinase kinase 2,MEK kinase kinase 2,MEKKK 2,Mitogen activated protein kinase kinase kinase kinase 2,Mitogen-activated protein kinase kinase kinase kinase 2,Rab8 interacting protein,Rab8 interacting protein,formerly,Rab8-interacting protein,RAB8IP,RAB8IP,formerly
Swissprot Q12851
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human MAP4K2
Application WB,ELISA
Recommended dilution WB 1:1000-1:5000
Concentration 0.3mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. 

 

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