MARVELD1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16594

Overview

Synonyms GB14,MALD1,MARVD1,MARVEL (membrane-associating) domain containing 1,MARVEL domain containing protein 1,MARVEL domain-containing protein 1,MARVELD1,MRVLDC1,Putative MARVEL domain containing protein 1
Swissprot Q9BSK0
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human MARVELD1
Application WB,IHC,ELISA
Recommended dilution WB 1:200-1:1000, IHC 1:50-1:200
Concentration 0.6mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background MARVELD1 (MARVEL domain containing 1), also known as GB14, MARVD1 or MRVLDC1, is a 173 amino acid protein that is widely expressed and contains one MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain. The MARVEL domain, which is common in Occludin proteins, is a 130 amino acid motif that contains four transmembrane helices, both of which have cytoplasmic N- and C-terminal regions. Localizing to the nucleus, MARVELD1 is downregulated in primary multiple tumors of liver, bladder, ovary, vulva, breast, testis, uterus, kidney and testis. The gene encoding MARVELD1 maps to human chromosome 10, whicHuman, Mouseakes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome and Cowden syndrome.

 

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