MITF Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-32037

Overview

Synonyms BHLHE32,bHLHe32,Class E basic helix-loop-helix protein 32,CMM8,Homolog of mouse microphthalmia,Mi,Microphthalmia associated transcription factor,Microphthalmia,mouse,homolog of,Microphthalmia-associated transcription factor,MITF,MITF,mitfa,nacre,WS2,WS2A,z3A.1
Swissprot O75030
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthesized peptide derived from human MITF around the non-phosphorylation site of Ser180.
Application WB,IHC-p,IF,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:50-1:300, IF 1:200-1:1000, ELISA 1:10000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

 

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